400-614-0008

Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein


Cat:MHC-HM431

Description

WT1 RMF.png
Synonyms:

MHC, WT1, RMF, Wilms tumor protein

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
WT1 RMF gel.png

Recombinant Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC
WT1 RMF HPLC.png

The purity of Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein was greater than 95% as determined by SEC-HPLC.

ELISA data
WT1 RMF ELISA.png

Immobilized Human HLA-A*0201 WT-1 (RMFPNAPYL) complex at 2ug/ml(100ul/Well). Dose response curve for Anti-WT1 complex mAb.with the EC50 of 193.9ng/ml determined by ELISA

Background

The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A*0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A*0201 of  the MHC Class I, B2M and RMFPNAPYL peptide of  the WT-1.

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