400-614-0008

Human 4-1BB/CD137 Protein


Cat:BB4-HM141

Description

4-1BB.png
Synonyms:

 CD137 antigen; CD137;TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CD137MGC2172; CDw137; FLJ43501; ILA; ILAhomolog of mouse 4-1BB; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; receptor protein 4-1BB; T cell antigen ILA; T-cell antigen 4-1BB homolog; T-cell antigen ILA; tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
4-1BB gel .png

Recombinant 4-1BB on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

HPLC Data
HPLC 4-1BB.png

The purity of 4-1BB (Cat. BB4-HM141) is greater than 95% as determined by SEC-HPLC.

ELISA data
无标题-ELISA2.jpg

Immobilized Human 4-1BB,His Tag (Cat.BB4-HM141) at 0.5ug/ml(100ul/Well). Dose response curve for Human 4-1BBL,Fc Tag (Cat.BBL-HM241) with the EC50 of 0.24ug/ml determined by ELISA..

Background

4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.

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