400-614-0008

Human CD80/B7-1 Protein


Cat:B71-HM280

Description

B7-1.png
Synonyms:

CD80 antigen; CD80 molecule; B7; B71; B7-1; Activation B7-1 antigen; BB1; CD28LG1; CD28LGB7-1 antigen); CD80; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; T-lymphocyte activation antigen CD80

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
B7-1 gel.png

Recombinant B7-1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

HPLC data
B7-1 HPLC.png

The purity of B7-1(Cat. B71-HM280) is greater than 95% as determined by SEC-HPLC

ELISA Data
CD80-ELISA.jpg

Immobilized human B7-1, Fc Tag (Cat. No. B71-HM280)  at 0.5 μg/mL (100 μL/well) can bind Human CTLA4,His Tag (Cat. No.CTL-HM141) with the EC50 of 78.9 ng/ml determined by ELISA.

Background

Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.

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