400-614-0008

Human B7-H4 Protein


Cat:BH7-HM174

Description

B7-H4.png
Synonyms:

B7H4; B7-H4; B7H4 T-cell costimulatory molecule B7x; B7S1; B7h.5; B7S1VCTN1; B7x; B7XPRO1291; FLJ22418; Immune costimulatory protein B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1; Vtcn1

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
B7-H4 gel.png

Recombinant B7-H4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

HPLC data
B7-H4 HPLC.png

The purity of B7-H4(Cat. BH7-HM174) is greater than 95% as determined by SEC-HPLC

ELISA Data
B7-H4-ELISA.jpg

Immobilized Human B7-H4,His tag at 0.5ug/ml(100ul/Well). Dose response curve for Anti-B7-H4 Ab. with the EC50 of 10.46ng/ml determined by ELISA.

Background

B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins.B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis . A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status .

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