betaKlotho; beta-klotho; BKL; KLB; klotho beta like; Klotho beta; klotho beta-like protein; MGC142213
Supplied as 0.22um filtered solution in PBS (pH 7.4).
The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.
Recombinant Human Beta Klotho Protein on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.
The purity of Human Beta Klotho is greater than 95% as determined by SEC-HPLC.
Immobilized Human Klotho at 1ug/ml(100ul/Well). Dose response curve for Anti-Klotho Ab.1 with the EC50 of 0.4ug/ml determined by ELISA.
Immobilized Human Klotho at 2ug/ml(100ul/Well).Dose response curve for Anti-Klotho Ab. 2 with the EC50 of 20.5ng/ml determined by ELISA.
Klotho is an anti-aging single-pass membrane protein predominantly produced in the kidney, with shedding of the amino-terminal extracellular domain into the systemic circulation. Circulating levels of soluble Klotho decrease with age, and the klotho gene is associated with increased risk of age-related diseases.