400-614-0008

Human CD3 epsilon & CD3 gamma Heterodimer Protein


Cat:CD3-HM157

Description

CD3E&CD3G-His.jpg
Synonyms:

CD3;CD3D;CD3-DELTA;T3D;CD3G

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
CD3E&CD3G-His-gel.jpg

Recombinant Human CD3 epsilon & CD3 gamma Heterodimer Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

HPLC Data
CD3E&CD3G-His-HPLC.jpg

Recombinant Human CD3 epsilon & CD3 gamma Heterodimer Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

ELISA data
CD3E&CD3G-His-ELISA.jpg

Immobilized Human CD3E&CD3G at 2ug/ml (100ul/Well). Dose response curve for Anti-CD3 Ab. with the EC50 of 0.86ug/ml determined by ELISA.

Background

T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.

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