Supplied as 0.22um filtered solution in PBS (pH 7.4).
The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.
Recombinant Human CD3 epsilon & CD3 gamma Heterodimer Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of Recombinant Human CD3 epsilon & CD3 gamma Heterodimer Protein was greater than 95% as determined by SEC-HPLC.
Immobilized Human CD3E&CD3G,Fc Tag at 0.5ug/ml (100ul/Well). Dose response curve for Anti-CD3E/CD3G Ab1.with the EC50 of 1.22ug/ml determined by ELISA.
Immobilized Human CD3E/CD3G at 0.1ug/ml (100ul/Well). Dose response curve for Anti-Human CD3E/CD3G Ab2.with the EC50 of 38ng/ml determined by ELISA.
Immobilized Human CD3E/CD3G,Fc Tag at 1ug/ml(100ul/Well).Dose response curve for Anti-Human CD3E/CD3G Ab.(OKT3) with the EC50 of 20.7/21.0/20.0ng/ml determined by ELISA.
Immobilized Human CD3E/CD3G at 1ug/ml(100μl/Well).Dose response curve for Anti-Human CD3E/CD3G Ab.with the EC50 of 20.7/19.5/20.0/20.7ng/ml determined by ELISA.
T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G , are single-pass type I membrane proteins.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.