400-614-0008

Biotinylated Human B7-H3b Protein


Cat:BH7-HM43BB

Description

KN130- BIO T.jpg
Synonyms:

B7H3; B7-H3; CD276 antigen; CD276 molecule; CD276; B7H34Ig-B7-H3; B7-H3B7 homolog 3; Costimulatory molecule

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
KN130-BIO GEL.jpg

Biotinylated Recombinant Human B7-H3b Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC
KN130-BIO HPLC.jpg

The purity of Biotinylated Recombinant Human B7-H3b Protein is greater than 95% as determined by SEC-HPLC.

Background

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma ) production, and cytotoxic T cells induction.

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