400-614-0008

Human FGFR2 (IIIb) domain2-3 Protein


Cat:FGF-HM12D

Description

KN300-T.jpg
Synonyms:

FGFR-2; KGFR; Keratinocyte growth factor receptor; CD332; BEK; KSAM

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
KN300-GEL.jpg

Recombinant Human FGFR2 (IIIb) domain2-3 Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC
KN300-HPLC.jpg

The purity of Recombinant Human FGFR2 (IIIb) domain2-3 Protein is greater than 95% as determined by SEC-HPLC.

Background

Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha  isoform, or only IgII and IgIII, referred to as the beta  isoform.

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