FGFR-2; KGFR; Keratinocyte growth factor receptor; CD332; BEK; KSAM
Supplied as 0.22um filtered solution in PBS (pH 7.4).
The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.
Recombinant Human FGFR2 (IIIb) domain2-3 Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.
The purity of Recombinant Human FGFR2 (IIIb) domain2-3 Protein is greater than 95% as determined by SEC-HPLC.
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha isoform, or only IgII and IgIII, referred to as the beta isoform.