400-614-0008

Human IL17A&F Protein


Cat:ILF-HM118

Description

KT444-D-T.jpg
Synonyms:

IL-17A,Interleukin-17A,CTLA-8,IL-17,IL-17F,IL24,ML-1,Interleukin-17F

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
KT444-D-GEL.jpg

Recombinant human IL17A&F Protein on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%.

SEC-HPLC
KT444-D-HPLC.jpg

The purity of Recombinant human IL17A&F Protein is greater than 95% as determined by SEC-HPLC.

Background

Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold .IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

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