400-614-0008

Human IL17A Protein


Cat:ILA-HM118

Description

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Synonyms:

CTLA-8; CTLA8cytotoxic T-lymphocyte-associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL17; IL-17; IL17A; IL-17A; IL-17Acytotoxic T-lymphocyte-associated protein 8; IL-17CTLA-8; IL17interleukin-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
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Recombinant Human IL17A Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC
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The purity of Human IL17A Protein is greater than 95% as determined by SEC-HPLC.

Background

Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold .IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC . Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.

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