400-614-0008

Human TIGIT Protein


Cat:TIG-HM210

Description

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Synonyms:

TIGIT; VSIG9; VSTM3; WUCAM;T cell immunoreceptor with Ig and ITIM domains

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
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Recombinant Human TIGIT on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. 

SEC-HPLC
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The purity of Human TIGIT is greater than 95% as determined by SEC-HPLC.

ELISA Data
ELISA.jpg

Immobilized Biotinylated Human CD155,His Tag at 1μg/ml(100μl/Well) on Streptavidin precoated(5ug/well) plate .Dose response curve for Human TIGIT,Fc Tag with the EC50 of 5.3ng/ml determined by ELISA.

Background

TIGIT, also called Vstm3, Vsig9, and WUCAM, is a transmembrane protein in the CD28 family of the Ig superfamily proteins.IGIT is expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells.

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