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Human ErbB3/Her3 Protein


Cat:HER-HM403

Description

HER3.png
Synonyms:

ErbB3; ErbB-3; erbB3-S; HER3; HER3c-erbB-3;c-erbB3; EC 2.7.10; EC 2.7.10.1; LCCS2; lethal congenital contracture syndrome 2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; Proto-oncogene-like protein c-ErbB-3; receptor tyrosine-protein kinase erbB-3; Tyrosine kinase-type cell surface receptor HER3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
HER3 GEL.png

Recombinant Her3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

HPLC Data 
HER3 HPLC.png

The purity of Her3 is greater than 95% as determined by SEC-HPLC.

ELISA data
HER3 ELISA.png

Immobilized Human Her3 at 1ug/ml(100ul/Well). Dose response curve for Anti-Her3 Ab.,with the EC50 of 0.2ug/ml determined by ELISA.

Background

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).

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