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Biotinylated 2019 nCOV Spike RBD


Cat:COV-VM4BDB

Description

RBD-His-BIO T.jpg
Synonyms:

S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
RBD-His-BIO GEL.jpg

Biotinylated Recombinant 2019-nCoV S protein RBD on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC
RBD-His-BIO HPLC.jpg

The purity of Biotinylated 2019-nCoV S protein RBD is greater than 95% as determined by SEC-HPLC.

ELISA data
RBD-His-BIO ELISA.jpg

Immobilized Human ACE2,His Tag  at 1ug/ml(100ul/Well).Dose response curve for Biotinylated spike RBD,His Tag with the EC50 of 0.1ug/ml determined by ELISA.

Background

The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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