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Biotinylated 2019 nCOV Spike S1


Cat:COV-VM4S1B

Description

S1-His-BIO T.jpg
Synonyms:

S1 protein,Spike glycoprotein Subunit1,S glycoprotein Subunit1,Spike protein S1

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
S1-His-BIO GEL.jpg

Biotinylated Recombinant 2019-nCoV Spike S1 protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC
S1-His-BIO HPLC.jpg

The purity of Biotinylated 2019-nCoV Spike S1 is greater than 95% as determined by SEC-HPLC.

ELISA data
S1-His-BIO ELISA.jpg

Immobilized Biotinylated n-COV S1, His Tag at 1ug/ml (100ul/Well). Dose response curve for ACE2, Fc Tag with the EC50 of 81ng/ml determined by ELISA.

Background

The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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