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2019 nCOV Spike RBD


Cat:COV-VM3BD

Description

RBD-mFc-gel.jpg
Synonyms:

S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD

Formulation and Storage

Formulation:

Supplied as 0.22um filtered solution in PBS (pH 7.4).

Storage:

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data

Tris-Bis PAGE
RBD-mFc-gel2.jpg

Recombinant 2019 nCOV Spike RBD Protein on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

HPLC Data
RBD-mFc-HPLC.jpg

The purity of 2019 nCOV Spike RBD is greater than 95% as determined by SEC-HPLC.

ELISA data
RBD-mFc-ELISA2.jpg

Immobilized n-CoV RBD,mFc Tag at 0.5ug/ml(100ul/Well). Dose response curve for Human ACE2,Fc Tag with the EC50 of 18.7 ng/ml determined by ELISA.

Background

The spike protein (S) of coronavirus (CoV) attaches the virus to its cellular receptor, angiotensin-converting enzyme 2 (ACE2). A defined receptor-binding domain (RBD) on S mediates this interaction.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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