Bulk Quote Inquiry

ANG-HM1L4-100μg / Inquiry

ANG-HM1L4-500μg / Inquiry

ANG-HM1L4-1mg / Inquiry

Human ANGPTL4/Angiopoietin-like 4 Protein

Product Info
Source

Recombinant Human ANGPTL4/Angiopoietin-like 4 Protein is expressed from Expi293 with His tag at the N-terminal. It contains Pro166-Ser406.[Accession | Q9BY76-1]

Molecular Weight

The protein has a predicted MW of 28.2 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.

Endotoxin

Less than 1EU per μg by the LAL method.

Purity

> 95% as determined by Tris-Bis PAGE
> 95% as determined by HPLC

Formulation

Supplied as 0.22μm filtered solution in PBS (pH 7.4).

Storage

The product should be stored at -70℃. Please do not repeated freeze-thaw cycles.

Assay Data
Tris-Bis PAGE

Human Angiopoietin-like 4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human Angiopoietin-like 4 is greater than 95% as determined by SEC-HPLC.

SPR Data

Human LILRB2 captured on Protein A chip, can bind Human ANGPTL4,His Tag with an affinity constant of 13.8nM as determined in a SPR assay (Biacore T200).

Background

Candidates for this common regulatory system include signals mediated by peroxisome proliferator-activated regulator and its response factor, angiopoietin-like 4. The expression and bioactivity of angiopoietin-like 4, an adipocytokine that was originally reported to have an angiogenic function, have been detected not only in the vascular system and adipose tissue but also in rheumatoid joints.

Synonyms

ANGPTL4;ARP4;FIAF;HFARP;Angiopoietin like 4

References

(1) Masuko K. Angiopoietin-like 4: A molecular link between insulin resistance and rheumatoid arthritis. J Orthop Res. 2017 May;35(5):939-943. doi: 10.1002/jor.23507. Epub 2017 Mar 8. PMID: 28004425.

Kactus Biosystems Co.Ltd
Online Message