Bulk Quote Inquiry

CDD-HM101-100μg / Inquiry

CDD-HM101-500μg / Inquiry

CDD-HM101-1mg / Inquiry

Human CD3D/CD3 delta Protein

Product Info
Source

Recombinant Human CD3D/CD3 delta Protein is expressed from Expi293 with His tag at the C-terminal. It contains Phe22-Ala105.[Accession | P04234]

Molecular Weight

The protein has a predicted MW of 10.4 kDa. Due to glycosylation, the protein migrates to 15 kDa based on Tris-Bis PAGE result.

Endotoxin

Less than 1EU per μg by the LAL method.

Purity

> 95% as determined by Tris-Bis PAGE

Formulation

Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.

Reconstitution

Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

Storage

The product should be stored at -70℃ or -20℃.

Assay Data
Tris-Bis PAGE

Human CD3 delta on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC

The purity of Human CD3 delta Protein is greater than 95% as determined by SEC-HPLC.

Background

T-cell surface glycoprotein CD3 delta chain, also known as CD3D, is a single-pass type I membrane protein.In immunology, the CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains.

Synonyms

CD3d;T-cell surface glycoprotein CD3 delta chain

References

(1)Penaranda C , Tang Q , Bluestone J A . Anti-CD3 Therapy Promotes Tolerance by Selectively Depleting Pathogenic Cells while Preserving Regulatory T Cells[J]. The Journal of Immunology, 2011, 187(4):2015-2022.

Kactus Biosystems Co.Ltd
Online Message