Immune Checkpoint Proteins

Immune blockade therapy has been becoming a new weapon in fighting cancer due to the development of immune checkpoint proteins targeting in cancer, especially after the success of antibody drugs targeting programmed cell death-1 (PD-1), programmed cell death ligand-1 (PD-L1) and cytotoxic T-lymphocyte antigen-4 (CTLA-4).
Although immune checkpoint blockade therapy often leads to more durable response than chemo or targeted therapies in some cases, clinical data shows its bottleneck that in most cancers, the response rate is low (10-30%). Therefore, more associated studies focus on the mechanisms of non-responsiveness, as well as finding new targeting strategies using other immune checkpoint proteins.
Based on our featured SAMSTM platform, Kactus has developed a series of immune checkpoint proteins with multiple pre-labels.
Product List
Cat. No. Protein Name Species Tag Exp. System
2B4-HM101 Human 2B4/CD244/SLAMF4 Protein Human C-His Expi293 Inquiry Now
BB4-HM141 Human 4-1BB/CD137 Protein Human C-His Expi293 Inquiry Now
LIL-HM4B1 Human LILRB1/CD85j/ILT2 Protein Human C-His-Avi Expi293 Inquiry Now
LIL-HM4B2 Human LILRB2/CD85d/ILT4 Protein Human C-His-Avi Expi293 Inquiry Now
LIL-HM4B4 Human LILRB4/CD85k/ILT3 Protein Human C-His-Avi Expi293 Inquiry Now
BH7-HM173 Human B7-H3/CD276 Protein Human C-His Expi293 Inquiry Now
BH7-HM174 Human B7-H4 Protein Human C-His-Avi Expi293 Inquiry Now
BH7-HM43B Human B7-H3 (4Ig)/B7-H3b Protein Human C-His-Avi Expi293 Inquiry Now
B72-HM486 Human CD86/B7-2 Protein Human C-His-Avi Expi293 Inquiry Now
CD8-HM428 Human/Cynomolgus/Rhesus macaque CD28 Protein Human / Cynomolgus / Rhesus macaque N-His-Avi Expi293 Inquiry Now
CD4-HM401 Human CD4/LEU3 Protein Human C-His-Avi Expi293 Inquiry Now
CD7-HM147 Human CD47 Protein Human C-His Expi293 Inquiry Now
SRP-HM172 Human SIRP alpha/CD172a Protein Human C-His Expi293 Inquiry Now
SRP-HM40B Human SIRP Beta/CD172b Protein Human C-His-Avi Expi293 Inquiry Now
SRP-HM40G Human SIRP Gamma/CD172g Protein Human C-His-Avi Expi293 Inquiry Now
CD1-HM455 Human CD155/PVR Protein Human C-His-Avi Expi293 Inquiry Now
DAM-HM101 Human DNAM-1/CD226 Protein Human C-His-Avi Expi293 Inquiry Now
NEC-HM402 Human Nectin-2/CD112 Protein Human C-His-Avi Expi293 Inquiry Now
NEC-HM404 Human Nectin-4 Protein Human C-His-Avi Expi293 Inquiry Now
PVR-HM301 Human PVRIG Protein Human C-mFc Expi293 Inquiry Now
TIG-HM110 Human TIGIT Protein Human C-His Expi293 Inquiry Now
OX4-HM440 Human OX40/TNFRSF4 Protein Human C-His-Avi Expi293 Inquiry Now
GTR-HM101 Human GITR/TNFRSF18 Protein Human C-His Expi293 Inquiry Now
BTL-HM401 Human BTLA Protein Human C-His-Avi Expi293 Inquiry Now
HVE-HM111 Human HVEM/TNFRSF14 Protein Human C-His Expi293 Inquiry Now
PD1-HM101 Human PD-1/PDCD1 Protein Human C-His Expi293 Inquiry Now
PDL-HM110 Human PD-L1/B7-H1 Protein Human C-His Expi293 Inquiry Now
More products from our catalog
Kactus Biosystems Co.Ltd
Online Message