Product Description |
Recombinant Biotinylated Human PGLYRP1 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-terminus.It contains Gln22-Pro196. |
Product Background |
Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
PGLYRP1 |
Synonyms |
PGRP-S; PGLYRP1; PGLYRP; PGRP; TNFSF3L; PGRP-SMGC126894; PGRPSMGC126896; TAG7; Tasg7 |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Gln22-Pro196 |
Molecular Weight |
The protein has a predicted MW of 21.04 kDa. Due to glycosylation, the protein migrates to 26-35 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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