Cynomolgus Activin RIIA/ACVR2A Protein (ARA-CM12A)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
  • Activity: Immobilized Human Activin A, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus Activin RIIA, His Tag with the EC50 of 75.0ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ala20-Pro135
Catalog #ARA-CM12A
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Product Description
 Recombinant Cynomolgus Activin RIIA/ACVR2A Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ala20-Pro135.
Product Background
 Activin A receptor type 2A (ACVR2A) is a membrane receptor in the transforming growth factor- beta (TGF-β signaling pathway, which is involved in the regulation of cell proliferation, migration, and apoptosis. Loss of ACVR2A has an important role in cancer progression and distant metastasis and may serve as a prognostic marker in patients with colon cancer.
Product Category
 Recombinant Protein
Target
 Activin RIIA/ACVR2A
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Ala20-Pro135
Molecular Weight
 The protein has a predicted MW of 15.02 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human Activin A, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus Activin RIIA, His Tag with the EC50 of 75.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag
 C-His
Express System
 HEK293
Purity
 >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin
 Less than 1EU per ug by the LAL method.
Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human Activin A, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus Activin RIIA, His Tag with the EC50 of 75.0ng/ml determined by ELISA (QC Test).
Cynomolgus Activin RIIA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus Activin RIIA is greater than 95% as determined by SEC-HPLC.
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