Human DLL4 Protein (DLL-HM104)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
Activity: Immobilized Human DLL4, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DLL4 Antibody, hFc Tag with the EC50 of 11.8ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Ser27-Pro524

Catalog: DLL-HM104

Order now get it on

Bulk Quote | Test Sample

Product Description	Recombinant Human DLL4 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser27-Pro524.
Product Background	Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate.
Product Category	Recombinant Protein

Target	DLL4
Gene/Protein ID	KT340-D
Species	Human
Exact Sequence	Ser27-Pro524
Molecular Weight	The protein has a predicted MW of 55.38 kDa. Due to glycosylation, the protein migrates to 56-70 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human DLL4, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DLL4 Antibody, hFc Tag with the EC50 of 11.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 200 mM L-Arginine (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human DLL4, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DLL4 Antibody, hFc Tag with the EC50 of 11.8ng/ml determined by ELISA.
	The purity of Human DLL4 is greater than 90% as determined by SEC-HPLC.
	Human DLL4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.