Product Description |
Recombinant Human FcRH5/FcRL5 Domain Protein is expressed from HEK293 with His tag and Avi tag at the N-terminus.It contains Val745-Thr850. |
Product Background |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
Product Category |
Recombinant Protein |
Target |
FcRH5/FcRL5 Domain |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Val745-Thr850 |
Molecular Weight |
The protein has a predicted MW of 14.0 kDa. Due to glycosylation, the protein migrates to 25-40 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-His-Avi |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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