Name: Human IL-31 RA Protein, Ultra Low Endotoxin (ILR-HM1RA-UL)
Brand: KactusBio
SKU: ILR-HM1RA-UL-100UG
Price: 381.0 USD
Availability: InStock

Human IL-31 RA Protein, Ultra Low Endotoxin (ILR-HM1RA-UL)

Human IL-31, His Tag immobilized on CM5 Chip can bind Human IL-31 RA, His Tag with an affinity constant of 125.61 nM as determined in SPR assay (Biacore T200).

Immobilized Human IL-31 RA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 4.7 ng/ml determined by ELISA (QC Test).

Human IL-31 RA-on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-31 RA-is greater than 90% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Human IL-31 RA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 4.7 ng/ml determined by ELISA (QC Test). The affinity constant of 125.61 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ala20-Glu519

Catalog #ILR-HM1RA-UL

Size

100UG

500UG

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Product Description	Recombinant Human IL-31 RA-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala20-Glu519.
Product Background	Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex for IL-31 together with the beta subunit of oncostatin M receptor (OSMR beta). OSMR beta is expressed in a subset of small-sized nociceptive neurons of adult dorsal root ganglia (DRGs). IL-31 and OSM may thus have redundant functions in the development of OSMRbeta-expressing neurons.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-31 RA
Synonyms	IL-31RA; IL-31R-alpha; Gp130-like receptor; CRL3; GPL; ZcytoR17; GLM-R; CRL3Glmr; GLM-RMGC125346; PRO21384
Accession	Q8NI17-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala20-Glu519
Molecular Weight	The protein has a predicted MW of 58.2 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-31 RA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 4.7 ng/ml determined by ELISA (QC Test). The affinity constant of 125.61 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 0.01 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-31, His Tag immobilized on CM5 Chip can bind Human IL-31 RA, His Tag with an affinity constant of 125.61 nM as determined in SPR assay (Biacore T200).
	Immobilized Human IL-31 RA, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-IL-31 RA Antibody, hFc Tag with the EC50 of 4.7 ng/ml determined by ELISA (QC Test).
	Human IL-31 RA-on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-31 RA-is greater than 90% as determined by SEC-HPLC.