Product Description |
Recombinant Human MMP-14 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Tyr112-Ala541. |
Product Background |
MMP-14 (also known as MT1-MMP) is a membrane-bound collagenase and member of the Matrix Metalloprotease (MMP) family known to target a broad range of extracellular matrix (ECM) proteins. MMP-14 can affect this regeneration via activation of other MMPs (MMP-2, -9 and -13) as well as cytokines, chemokines and growth factors. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
MMP-14 |
Synonyms |
MMP14; MMP-X1; MMP X1; MT-MMP 1; MTMMP1; MT1-MMP; MT1MMP; |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Tyr112-Ala541 |
Molecular Weight |
The protein has a predicted MW of 50.78 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 25mM Tris, 150mM NaCl (pH 7.5). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human MMP-14 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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