Biotinylated Human KIR2DL2 Protein (KIR-HM4L2B)
Catalog: KIR-HM4L2B
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| Product Description | Recombinant Biotinylated Human KIR2DL2 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His22-His245. |
Product Background |
KIR2DL2 (2DL2, formerly NKAT6, designated CD158b) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like receptor (KIR) family. KIRs are expressed on human CD56dim NK cells and T cell subsets, and regulate effector functions in the innate immune system.KIR2DL2 is receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis. |
Product Category |
Recombinant Protein |
Target |
KIR2DL2 |
| Synonyms | Killer cell immunoglobulin-like receptor 2DL2；CD158 antigen-like family member B1；MHC class I NK cell receptor；NKAT-6；p58 NK receptor CL-43；CD158b1；KIR2DL2；CD158B1；NKAT6 |
Gene/Protein ID |
P43627 |
Species |
Human |
Exact Sequence |
His22-His245 |
| Molecular Weight | The protein has a predicted MW of 27.4 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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The purity of Biotinylated-Human KIR2DL2 is greater than 90% as determined by SEC-HPLC. |
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Biotinylated Human KIR2DL2 on Tris-Bis PAGE under reduced conditions. The purity is greater than 95%. |
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