Our Mission
Provide first-to-market recombinant protein and enzymes to accelerate novel biopharma and diagnostic breakthroughs.
Our Roots
Protein design and expression grounded in proven structural biology techniques.
Our Method
Extensive support through reliable and consistent customer service and fast, dependable shipping
Product Focus Areas
MHC Monomers & Tetramers
Antibody Target Proteins
Gene Editing Reagents
RNA Synthesis Enzymes
Cell Therapy Proteins
Our highly curated catalog is based on:
Unmet Needs
The products available in our catalog have been carefully chosen based on the current research demands. This includes products fulfilling unaddressed market segments and overlooked consumer needs. To keep pace with the ever-evolving scientific landscape, our catalog dynamically adapts, which is why we introduce new products every month.
Product Quality
We pride ourselves on our commitment to protein and enzyme quality. Our products undergo rigorous analysis for purity, bioactivity, endotoxin, etc. using reliable analytical methods including SEC-HPLC, SPR, ELISA, and biochemical assays. Only products meeting our stringent quality standards are selected for inclusion in our catalog.
Reliability of Supply
With over 15,000 square meters of state-of-the-art manufacturing facilities, we ensure a dependable and continuous supply of products from our catalog, including bulk quantities as needed, to meet our clients' demands consistently and efficiently.
Why choose KACTUS?
Consistent bioactivity & stability
ELISA/SPR bioactivity validation
Greater than 95% Purity via SEC-HPLC & Bis-Tris Page
Batch-to-batch consistency
Long-term and accelerated stability testing
Fast & reliable shipping
Same day order fulfillment from Boston, MA
Next-day order fulfillment
1-4 day shipping globally
Worldwide distributors
Highly responsive team
Scientific support regarding products & applications
Personalized customer service
Hear back from us within 1 business day...
..but probably sooner :)
Our History
→ MARCH 2018
Founded
Established in 2018, KACTUS embarked on its journey with a resolute mission: to deliver innovative solutions to the realm of recombinant proteins, squarely addressing the unmet demands of researchers and the challenges posed by intricate protein expression.
→ JULY 2018
First company to express Claudin 18.2
Our esteemed scientific team achieved a remarkable breakthrough by becoming the first to successfully express the intricate multi-transmembrane protein Claudin 18.2. This achievement showcased the robust capabilities of our protein engineering capabilities.
→ 2019
SAMS™ Technology Platform
Having diligently pursued the recombinant expression of numerous proteins including MHCs and transmembrane proteins, our endeavors culminated in the conceptualization of our pioneering protein technology platform, aptly named Structure-Aided Multiplex Screening (SAMS™).
→ 2020
Established GMP Enzyme Enterprise
In a significant stride forward, our transformation into a cGMP enzyme manufacturing facility in 2021 underscored our substantial commitment to commercialization solutions, enabling us to provide an extensive range of GMP-Grade mRNA and gene editing enzymes.
→ 2021
GMP Auditing & DMF Submissions
We achieved a significant milestone by passing onsite audits for our GMP-compliant facilities by esteemed clients in the gene editing and mRNA vaccine sectors. In alignment with our commitment to regulatory adherence and product quality, we took a proactive step by filing Drug Master Files (DMF) for our key GMP enzyme products. This initiative also underscored our unwavering focus on maintaining the highest standards of quality assurance.
→ FEBRUARY 2022
Making Products Accessible
In our quest to enhance accessibility to our products, we emphasized a global operational footprint, with international distributors, ready-to-ship products, and fast shipping speeds. Quality customer service is at the forefront of our logistics operations.
→ DECEMBER 2022
GMP Enzyme Approved for Clinical Trial
Our GMP-Grade CRISPR Cas9 Enzyme was not only approved for use in Reforgene Medicine's Clinical Trial to treat beta-thalassemia but also stands as a testament to the authenticity and credibility of our state-of-the-art production facilities and comprehensive regulatory support.
→ TODAY
Fueled by Purpose
Today, our solutions have expanded to include 2500+ recombinant proteins, 25+ GMP enzymes, and custom protein expression. We continue to launch new products and services to facilitate novel drug development, focusing on current challenges in R&D and commercialization.
Advanced Protein Engineering & Expression
SAMS™ Technology Platform
Our products are developed using our proprietary protein engineering platform, SAMS™: Structure Aided Multiplex Screening. 3D protein structures are optimized using advanced bioinformatics, structural analysis, and 3D modeling. Multiple protein constructs are tested in various expression conditions to optimize activity, yield, and configuration. With this platform we have produced difficult-to-express targets such as CCR8 and Claudin 18.2. We've also developed VLP-displayed antigens, MHC complexes, AAV ELISA kits, DNA Amplification enzymes, Laminin 521, and GMP-Grade mRNA and gene editing enzymes.
Advantages of SAMS™
Design Expertise
Our expertise in structural biology, protein design, and enzymatic studies, along with our SAMS™ platform, will help you create a protein configuration that will be functional for your application while also optimizing purity & yield.
Tailored Expression Systems
After generating 3D models of your protein/enzyme, we test the configurations in various expression systems to optimize protein folding, maximize bioactivity, and enhance stability.
Quality Bulk Supply
We'll take your protein configuration from bench to large-scale production. Our quality control systems ensure batch-to-batch consistency and our facilities are prepared for consistent high-quantity production.
Our Values
Quality
We strive to be a world-class biotechnology company, serving our global biopharma and diagnostics customers.
Communication
We value direct and open communication. We are problem-solvers and are responsive to constructive criticism.
Collaboration
We work together as a team toward our common goal. We contribute to the team, and we lean on the team for support
Endurance
Problems are our fuel for improvement. We value ambitious and independent people with a strong desire for success, self-development, and even material returns.
Ambition
We do not shy away from technological setbacks. We embrace novel design demands and first-to-market products.
ADDRESS
60 Hickory Drive
Waltham, MA 02451
United States
About KACTUS: Quality Recombinant Proteins and Enzymes