Cynomolgus CCL24 Protein (CCL-CM124)

Express System: HEK293
Product Tag: N-His
Purity: > 90% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
Activity: Immobilized Cynomolgus CCL24, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCL24 Antibody, hFc Tag with the EC50 of 46.8ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: His19-His119

Catalog: CCL-CM124

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Product Description	Recombinant Cynomolgus CCL24 Protein is expressed from HEK293 with His tag at the N-Terminus.It contains His19-His119.
Product Background	C-C motif chemokine ligand 24 (CCL24) is a chemokine that regulates inflammatory and fibrotic activities through its receptor, C-C motif chemokine receptor (CCR3). CCL24 is a chemokine that regulates inflammation and fibrosis. It was found to be significantly expressed in patients with non-alcoholic steatohepatitis, in whom it regulates profibrotic processes in the liver.
Product Category	Recombinant Protein

Target	CCL24
Gene/Protein ID	XP_005549400.1
Species	Cynomolgus
Exact Sequence	His19-His119
Molecular Weight	The protein has a predicted MW of 12.36 kDa. Due to glycosylation, the protein migrates to 23-38 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus CCL24, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCL24 Antibody, hFc Tag with the EC50 of 46.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His
Express System	HEK293
Purity	> 90% as determined by Tris-Bis PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus CCL24, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-CCL24 Antibody, hFc Tag with the EC50 of 46.8ng/ml determined by ELISA.
	The purity of Cynomolgus CCL24 is greater than 90% as determined by SEC-HPLC.
	Cynomolgus CCL24 on Tris-Bis PAGE under reduced condition. The purity is greater than 90%.