Cynomolgus ROR2/NTRKR2 Protein (ROR-CM102)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus ROR2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Glu34-Met402

Catalog: ROR-CM102

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Product Description	Recombinant Cynomolgus ROR2/NTRKR2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu34-Met402.
Product Background	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, including bone and cartilage formation, as well as for the development of the central nervous system. Mature human ROR2 contains a 369 amino acid (aa) extracellular domain (ECD) and a 518 aa cytoplasmic tail containing an tyrosine kinase domain.
Product Category	Recombinant Protein

Target	ROR2/NTRKR2
Gene/Protein ID	A0A7N9D5U8
Species	Cynomolgus
Exact Sequence	Glu34-Met402
Molecular Weight	The protein has a predicted MW of 42.29 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus ROR2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus ROR2, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-ROR2 Antibody, hFc Tag with the EC50 of 4.3ng/ml determined by ELISA.
	The purity of Cynomolgus ROR2 is greater than 95% as determined by SEC-HPLC.
	Cynomolgus ROR2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.