FITC-Labeled Human Siglec-3/CD33 Protein (CD3-HM433F)
Catalog: CD3-HM433F
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| Product Description | Recombinant FITC-Labeled Human Siglec-3/CD33 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp18-His259. |
Product Background |
Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.They are sialoadhesin/CD169/Siglec-1, CD22/Siglec-2, CD33/Siglec-3, Myelin-Associated Glycoprotein (MAG/Siglec-4a) and Siglecs 5 to 11. To date, no Siglec has been shown to recognized any cell surface ligand other than sialic acids, suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs. |
Product Category |
Recombinant Protein |
Target |
Siglec-3/CD33 |
| Synonyms | CD33 molecule; CD33; FLJ00391; gp67; Siglec3; Siglec-3; p67 |
Gene/Protein ID |
P20138-1 |
Species |
Human |
Exact Sequence |
Asp18-His259 |
| Molecular Weight | The protein has a predicted MW of 29.6 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22um filtered solution in 10mM NaH2PO4, 2mM EDTA, 500mM NaCl (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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FITC-Labeled Human Siglec-3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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