Human LRP1 (26-109) Protein (LRP-HM611)

Catalog #LRP-HM611

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$375.00

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Human LRP1 (26-109) Protein (LRP-HM611) Summary

Product Description	Recombinant Human LRP1 (26-109) Protein is expressed from HEK293 with His tag and Strep II tag at the C-terminus.It contains Thr26-Arg109.
Product Background	Low-density lipoprotein (LDL)-related protein-1 (LRP-1) is a member of LDL receptor family that is implicated in lipoprotein metabolism and in the homeostasis of proteases and protease inhibitors. In addition to its function as a scavenger receptor for various ligands, LRP-1 has been shown to transduce multiple intracellular signal pathways including mitogen-activated protein kinase (MAPK), Akt, Rho, and the integrin signaling. LRP-1 signaling plays an important role in the regulation of diverse cellular process, such as cell proliferation, survival, motility, differentiation, and transdifferentiation, and thus participates in the pathogenesis of organ dysfunction and injury.
Product Category	Recombinant Protein / Others / Other

Protein	LRP1
Synonyms	LRP-1; A2MR; APOER; CD91; APR; IGFBP3R1; IGFBP-3R; LRP1A; IGFBP3R; TGFBR5; DDH3; KPA
Accession	Q07954-1
Species	Human
Biotinylated	no
Amino Acid Range	Thr26-Arg109
Molecular Weight	The protein has a predicted MW of 11.74 kDa. Due to glycosylation, the protein migrates to 13-20 kDa based on Bis-Tris PAGE result.
Product Tag	C-His-Strep-II
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 10mM HEPES, 150mM NaCl, 5mM CaCl₂, 0.005% Tween-20 (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Human LRP1 (26-109) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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