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Human LRP1 (26-109) Protein (LRP-HM611) Summary
Product Description |
Recombinant Human LRP1 (26-109) Protein is expressed from HEK293 with His tag and Strep II tag at the C-terminus.It contains Thr26-Arg109. |
Product Background |
Low-density lipoprotein (LDL)-related protein-1 (LRP-1) is a member of LDL receptor family that is implicated in lipoprotein metabolism and in the homeostasis of proteases and protease inhibitors. In addition to its function as a scavenger receptor for various ligands, LRP-1 has been shown to transduce multiple intracellular signal pathways including mitogen-activated protein kinase (MAPK), Akt, Rho, and the integrin signaling. LRP-1 signaling plays an important role in the regulation of diverse cellular process, such as cell proliferation, survival, motility, differentiation, and transdifferentiation, and thus participates in the pathogenesis of organ dysfunction and injury. |
Product Category |
Recombinant Protein / Others / Other |
Human LRP1 (26-109) Protein (LRP-HM611) Specifications/Details
Protein |
LRP1 |
Synonyms |
LRP-1; A2MR; APOER; CD91; APR; IGFBP3R1; IGFBP-3R; LRP1A; IGFBP3R; TGFBR5; DDH3; KPA |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Thr26-Arg109 |
Molecular Weight |
The protein has a predicted MW of 11.74 kDa. Due to glycosylation, the protein migrates to 13-20 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His-Strep-II |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 10mM HEPES, 150mM NaCl, 5mM CaCl2, 0.005% Tween-20 (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human LRP1 (26-109) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
Other Available Proteins:
Finding available proteins...
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