Browse CD3 Proteins
Browse our popular CD3 proteins here or click below to view the full catalog selection:
We verified the activity of our heterodimers, such as CD3E/G-His Tag and CD3E/D-His Tag, via ELISA and SPR.
A proprietary design, expression, and purification system ensures the two subunits of the heterodimers are expressed in equal proportions with greater than 95% purity, verfied by SDS-PAGE and SEC-HPLC.
Our CD3 proteins have high batch-to-batch consistency and long-term stability as verified by ELISA.
CD3 (Cluster of differentiation 3) is one of the proteins expressed on the surface of T cells. It consists of six peptide chains, one γ chain, one δ chain, two ε chains and two ζ chains. These six peptide chains are all transmembrane, and the transmembrane region is connected with TCR through a salt bridge to form a tight TCR-CD3 complex, which jointly participates in the recognition and signal transduction of T cells to antigens. The activation signal generated by TCR recognition of antigen is transduced into T cells by the ITAM sequence in the cytoplasmic region of CD3, and then a series of immune responses are initiated.
Antibody Discovery
Immunization
Antibody Screening
Functional characterization
Affinity Determination (ELISA, SPR, BLI)
TCR/CD3 signaling (Louis-Dit-Sully C et. al, 2012)
KACTUS offers custom recombinant CD3 protein production.
Browse our popular CD3 proteins here or click below to view the full catalog selection:
from $600.00
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from $525.00
from $525.00
from $600.00
from $600.00
from $600.00
from $600.00
from $600.00
from $525.00