Human LRP1 (3333-3777) Protein (LRP-HM614)
  • Express System: HEK293
  • Product Tag: C-His-Strep-II
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Asn3333-Ser3777
Catalog #LRP-HM614
Regular price $375.00
/
Size
image image

Order by 4pm ET for delivery on:

Human LRP1 (3333-3777) Protein (LRP-HM614) Summary

Product Description

Recombinant Human LRP1 (3333-3777) Protein is expressed from HEK293 with His tag and Strep II tag at the C-terminus.It contains Asn3333-Ser3777.

Product Background

Low-density lipoprotein (LDL)-related protein-1 (LRP-1) is a member of LDL receptor family that is implicated in lipoprotein metabolism and in the homeostasis of proteases and protease inhibitors. In addition to its function as a scavenger receptor for various ligands, LRP-1 has been shown to transduce multiple intracellular signal pathways including mitogen-activated protein kinase (MAPK), Akt, Rho, and the integrin signaling. LRP-1 signaling plays an important role in the regulation of diverse cellular process, such as cell proliferation, survival, motility, differentiation, and transdifferentiation, and thus participates in the pathogenesis of organ dysfunction and injury.

Product Category

Recombinant Protein / Others / Other

Human LRP1 (3333-3777) Protein (LRP-HM614) Specifications/Details

Protein
LRP1
Synonyms
LRP-1; A2MR; APOER; CD91; APR; IGFBP3R1; IGFBP-3R; LRP1A; IGFBP3R; TGFBR5; DDH3; KPA
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Asn3333-Ser3777
Molecular Weight
The protein has a predicted MW of 52.32 kDa. The protein cleaved to 42-52 kDa and 65-85 kDa based on Bis-Tris PAGE result.
Product Tag
C-His-Strep-II

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 10mM HEPES, 150mM NaCl, 5mM CaCl2, 0.005% Tween-20 (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human LRP1 (3333-3777) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human LRP1 (3333-3777) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human LRP1 (3333-3777) is greater than 90% as determined by SEC-HPLC. The purity of Human LRP1 (3333-3777) is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Recently viewed