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Human LRP2 (27-308) Protein (LRP-HM621) Summary
Product Description |
Recombinant Human LRP2 (27-308) Protein is expressed from HEK293 with His tag and Strep II tag at the C-terminus.It contains Glu27-Ser308. |
Product Background |
Megalin (or LRP2) is an endocytic receptor that plays a central role in embryonic development and adult tissue homeostasis. Loss of this receptor in congenital or acquired diseases results in multiple organ dysfunctions, including forebrain malformation (holoprosencephaly) and renal reabsorption defects (renal Fanconi syndrome). |
Product Category |
Recombinant Protein / Others / Other |
Human LRP2 (27-308) Protein (LRP-HM621) Specifications/Details
Protein |
LRP2 |
Synonyms |
LRP-2; gp330; Megalin; Glycoprotein 330 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu27-Ser308 |
Molecular Weight |
The protein has a predicted MW of 33.64 kDa. Due to glycosylation, the protein migrates to 52-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His-Strep-II |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 10mM HEPES, 150mM NaCl, 5mM CaCl2, 0.005% Tween-20 (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
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Human LRP2 (27-308) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human LRP2 (27-308) is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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