Human LRP2 (3511-3963) Protein (LRP-HM624)
  • Express System: HEK293
  • Product Tag: C-His-Strep-II
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Met3511-Asn3963
Catalog #LRP-HM624
Regular price $375.00
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Size
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Human LRP2 (3511-3963) Protein (LRP-HM624) Summary

Product Description

Recombinant Human LRP2 (3511-3963) Protein is expressed from HEK293 with His tag and Strep II tag at the C-terminus.It contains Met3511-Asn3963.

Product Background

Megalin (or LRP2) is an endocytic receptor that plays a central role in embryonic development and adult tissue homeostasis. Loss of this receptor in congenital or acquired diseases results in multiple organ dysfunctions, including forebrain malformation (holoprosencephaly) and renal reabsorption defects (renal Fanconi syndrome).

Product Category

Recombinant Protein / Others / Other

Human LRP2 (3511-3963) Protein (LRP-HM624) Specifications/Details

Protein
LRP2
Synonyms
LRP-2; gp330; Megalin; Glycoprotein 330
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met3511-Asn3963
Molecular Weight
The protein has a predicted MW of 53.66 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.
Product Tag
C-His-Strep-II

Fluorophore

Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 10mM HEPES, 150mM NaCl, 5mM CaCl2, 0.005% Tween-20 (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human LRP2 (3511-3963) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human LRP2 (3511-3963) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human LRP2 (3511-3963) is greater than 95% as determined by SEC-HPLC. The purity of Human LRP2 (3511-3963) is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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