• Express System: HEK293
  • Product Tag: N-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ala30-Ile710
Catalog #QSX-HM201
Price
Regular price $34500
Regular price Sale price $34500
/
Size
Avantor VWR Fisher Scientific

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Human QSOX1 Protein (QSX-HM201) Summary

Product Description

 Recombinant Human QSOX1 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-terminus.It contains Ala30-Ile710.

Product Background

 Quiescin sulfhydryl oxidase 1 (QSOX1) is a disulfide bond-forming enzyme with both disulfide isomerase and oxidoreductase activities. It plays an important role in protein folding, stability, and secretion. QSOX1 is upregulated in many cancers through a combination of genetic, transcriptional, microenvironmental, and post-transcriptional mechanisms. Functionally, QSOX1 can promote tumor progression by enhancing matrix metalloproteinase activity, supporting cancer cell survival under oxidative stress, regulating ECM assembly, and fostering immune-suppressive tumor microenvironments.

Human QSOX1 Protein (QSX-HM201) Specifications/Details

Protein
 QSOX1
Synonyms
 QSCN6; Q6; QSOX-L
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ala30-Ile710
Molecular Weight
 The protein has a predicted MW of 101.55 kDa. Due to glycosylation, the protein migrates to 110-140 kDa based on Bis-Tris PAGE result.
Product Tag
 N-hFc (IgG1)
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human QSOX1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human QSOX1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human QSOX1 is greater than 95% as determined by SEC-HPLC. The purity of Human QSOX1 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...