Name: Mouse IL-23R Protein (ILR-MM123)
Brand: KactusBio
SKU: ILR-MM123-100UG
Price: 330.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 6.31 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gly24-Gly374

Catalog #ILR-MM123

Size

100UG

500UG

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Product Description	Recombinant Mouse IL-23R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly24-Gly374.
Product Background	Interleukin-23 (IL-23), a member of the IL-12 family of cytokines, is a heterodimeric cytokine. It is composed of subunits p40 (shared with IL-12) and p19 (an IL-12 p35-related subunit) and is secreted by several types of immune cells, such as natural killer cells and dendritic cells. The IL-23 receptor is composed of the subunit IL-12Rβ1 and the IL-23-specific subunit IL-23R. The binding of IL-23 to its specific cell surface receptor regulates a number of functions, including proliferation and differentiation of cells and secretion of cell factors.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-23R
Synonyms	IBD17; IL-23 R; IL-23 receptor; Il23r; Interleukin-23 receptor
Accession	Q8K4B4
Species	Mouse
Biotinylated	no
Amino Acid Range	Gly24-Gly374
Molecular Weight	The protein has a predicted MW of 41.48 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 6.31 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse IL-23R, His Tag immobilized on CM5 Chip can bind Mouse IL-23 alpha&IL-12 beta, His Tag with an affinity constant of 6.31 nM as determined in SPR assay (Biacore T200).
	Mouse IL-23R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse IL-23R is greater than 95% as determined by SEC-HPLC.