Articles on MHC & TCR
The interaction between MHC molecules and T-cell receptors (TCRs) is central to immune system function and therapeutic design. This category highlights key developments in MHC/TCR research, immunotherapy strategies, and biotech-driven solutions.
Featured Article
TCR Therapy Targeting MAGE-A4
Recently at the 2022 CTOS Conference, Adaptimmune announced the SPEARHEAD-1 clinical trial data of its T cell receptor-engineered T cell (TCR-T) therapy, Afamitresgene autoleucel (afami-cel), for synovial sarcoma. The results showed that the overall response rate of afami-cel was 39% and the median duration of response was 50 weeks [1].
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December 27, 2023
5 min read
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MHC & TCR Research in Immunotherapy