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FEATURED ARTICLE

MASP2 Antibody Successful in Phase III Clinical Trial

On December 19, 2024, Omeros announced that its pivotal Phase 3 clinical trial of the MASP2 antibody Narsoplimab (OMS721) in the treatment of TA-TMA (Transplant-Associated Thrombotic Microangiopathy) met its primary endpoint of overall survival (OS), with a 3-fold reduction in mortality risk [1]. Omeros stock surged 37% after the press release...

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MASP2 Antibody Successful in Phase III Clinical Trial

February 10, 2025

5 min read

On December 19, 2024, Omeros announced that its pivotal Phase 3 clinical trial of the MASP2 antibody Narsoplimab (OMS721) in...

Immunotherapy Target: CD19 Antigen

February 4, 2025

7 min read

CD19 remains a hot target in immunotherapy, driving innovation across a range of diseases. This is evidenced by recent approvals...

Case Review: Exploring domain proteins in antibody development

January 22, 2025

7 min read

Domain Antigens for Antibody Discovery & Screening The antibody drug development underwent rapid progress over the past decade, with almost...

Emerging New Therapeutic Targets for Obesity

January 14, 2025

7 min read

Obesity is increasingly undermining human health. Obesity, a chronic metabolic disease, has significantly impacted the health and quality of life...

Activin Signaling Pathway: Therapeutic Potential Across Disease Frontiers

November 25, 2024

7 min read

What if a single cellular pathway could unlock new therapies for muscle regeneration, cancer, obesity, immune system regulation, and more?...

MRGPRX2: A Promising Target for Antibody Discovery in Allergy and Pain Disorders

October 28, 2024

5 min read

Recent studies have shown that various drugs, including small molecules, opioids, and antibiotics, can activate MRGPRX2 (Mas-related G-protein coupled receptor...

VLP Antibody Discover

October 2, 2024

4 min read

How VLPs are unlocking the next generation of antibody therapeutics for challenging transmembrane proteins Transmembrane proteins play crucial roles in...

Virus-Like Particles (VLPs): Understanding their Structure, Expression, and Role in Immune Response

August 28, 2024

7 min read

What are virus-like particles (VLPs)? Virus-like particles (VLPs) are nanoparticle structures (50-300nm diameter) that mimic the organization and conformation of...

MSLN Targeted Drugs Entering the Fast Lane

February 29, 2024

5 min read

Since December 2023, there have been several positive updates about drugs targeting MSLN. On December 19th, RemeGen announced that the...

Butyrophilin (BTN) family: γδ T Cell Receptor Ligands, Immunomodulators and More

December 27, 2023

5 min read

Immunotherapy is an essential option for current disease treatment. However, most patients fail to respond adequately to existing immunotherapies, such...

The Role of Delta-like Ligand 3 (DLL3) in Targeted Therapy for Cancer

November 27, 2023

5 min read

  On November 13, 2023, Legend Biotech officially announced that its wholly-owned subsidiary, Legend Biotech Ireland Limited, has entered into...

Cell and Antibody Therapies Targeting HLA-G

February 14, 2023

3 min read

On December 19, 2022, the FDA approved the Phase I/IIa clinical trial application of IVS-3001, an anti-HLA-G Chimeric Antigen Receptor-T...

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