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Immunotherapy Target: CD19 Antigen

CD19 remains a hot target in immunotherapy, driving innovation across a range of diseases. This is evidenced by recent approvals for new treatments in multiple sclerosis and leukemia and a major acquisition in the bispecific antibody space...

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Cracking KRAS: How TCR-T and TCR-Mimic Antibodies Are Changing KRAS Mutant Cancers

March 18, 2025

9 min read

Introduction Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most frequently mutated oncogenes in human cancer​ [1]. Mutations in...

Breaking News: KACTUS GMP-Grade Cas9 Powers Bioheng’s Breakthrough IND Clearance for Next-Gen UCAR-T Therapy

March 5, 2025

4 min read

KACTUS is thrilled to announce that our GMP-Grade Cas9 enzyme is playing a pivotal role in the development of Bioheng Therapeutics'...

Immunotherapy Target: CD19 Antigen

February 4, 2025

7 min read

CD19 remains a hot target in immunotherapy, driving innovation across a range of diseases. This is evidenced by recent approvals...

NK Cell Therapy Gets IND FDA Clearance with AccuBase® Base Editor from KACTUS

November 21, 2024

5 min read

November 14, 2024 Base Therapeutics announced that its independently developed NK510 cell injection, the world's first base-edited universal NK cell...

2024 Milestones in CRISPR Clinical Pipelines

November 11, 2024

6 min read

With the first CRISPR gene-editing drug approved for over ten months now, what exciting developments are there in CRISPR drug...

MSLN Targeted Drugs Entering the Fast Lane

February 29, 2024

5 min read

Since December 2023, there have been several positive updates about drugs targeting MSLN. On December 19th, RemeGen announced that the...

Base Editing Technology Leads a New Chapter in Drug Development

February 14, 2024

5 min read

Since its debut in 2016, base editing technology has opened up new perspectives and methods for drug development with its...

Cell and Antibody Therapies Targeting HLA-G

February 14, 2023

3 min read

On December 19, 2022, the FDA approved the Phase I/IIa clinical trial application of IVS-3001, an anti-HLA-G Chimeric Antigen Receptor-T...

TCR Therapy Targeting MAGE-A4

January 2, 2023

1 min read

Recently at the 2022 CTOS Conference, Adaptimmune announced the SPEARHEAD-1 clinical trial data of its T cell receptor-engineered T cell...

CDH17: A Safe CAR-T Target for Treatment of Solid Tumors

July 19, 2022

5 min read

Chimeric antigen receptor T cell (CAR-T) therapy has been successful in the field of hematological malignancies, but it is not...

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