Name: FITC-Compatible Human CD19 Protein (CD1-HM119F)
Brand: KactusBio
SKU: CD1-HM119F-100UG
Price: 900.0 USD
Availability: InStock

FITC-Compatible Human CD19 Protein (CD1-HM119F)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Pro20-Lys291

Catalog #CD1-HM119F

Size

100UG

500UG

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Product Description	FITC-Compatible Human CD19 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro20-Lys291.
Product Background	CD19 is a B-lineage-specific transmembrane glycoprotein, the expression of which is maintained on more than 95% B-cell malignancies. This strict lineage restriction makes CD19 an ideal target for immune therapies using chimeric antigen receptors (CARs). T cells engineered to express a chimeric antigen receptor (CAR) against CD19 have recently been FDA approved for the treatment of relapsed or refractory large B-cell lymphoma. Despite the success and curative potential of CD19 CAR T cells, several reports describing disease relapse due to antigen loss are now emerging.
Product Category	Recombinant Protein

Target	FITC-Compatible CD19
Synonyms	CD19; B4; CVID3; Leu-12; MGC12802
Accession	P15391-1
Species	Human
Biotinylated	no
Amino Acid Range	Pro20-Lys291
Molecular Weight	The protein has a predicted MW of 60.1 kDa. Due to glycosylation, the protein migrates to 68-72 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Fluorophore	FITC
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	FITC-Compatible Human CD19 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Use 100 ul FITC-Compatible Human CD19 (10 ug/ml) to detect the positive rate of 1×10⁶ anti-CD19 CAR cells and FITC-labeled irrelevant protein (100 ul, 10 ug/ml) was served as a negative control.
	The purity of FITC-Compatible Human CD19 is greater than 95% as determined by SEC-HPLC.

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