Recombinant Glypican-3: GPC3
7 products
Background
Glypican-3, encoded by the GPC3 gene in humans, is a protein composed of two core subunits. The N-terminal subunit has an approximate size of 40 kDa, while the C-terminal subunit is around 30 kDa. This protein holds promise as a therapeutic target for the treatment of various cancers, including liver cancer. Researchers have developed several therapeutic antibodies targeting GPC3 to explore its potential in cancer therapy.
Synonyms
Glypican-3; GPC3; DGSX; Glypican 3; GTR2-2; MXR7; OCI5; OCI-5; SGB; SGBS; SGBS1SDYS; SDYS; SGBS1
Performance Validation
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Immobilized Human GPC3 VLP at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GPC3 Antibody, hFc Tag with the EC50 of 20.2ng/ml determined by ELISA. |
Immobilized Anti-GPC3 Antibody, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human GPC3, His Tag with the EC50 of 10.8ng/ml determined by ELISA. |
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Immobilized Cynomolgus GPC3, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPC3 Antibody, hFc Tag with the EC50 of 35.0ng/ml determined by ELISA. |
The purity of Biotinylated Human GPC3 is greater than 95% as determined by SEC-HPLC. |
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