Name: Biotinylated Human CCR5 Protein-Nanodisc (CR5-HM4N191B)
Brand: KactusBio
SKU: CR5-HM4N191B-100UG
Price: 1875.0 USD
Availability: InStock

Biotinylated Human CCR5 Protein-Nanodisc (CR5-HM4N191B)

Immobilized Biotinylated Human CCR5 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR5 Antibody, hFc Tag with the EC50 of 0.20ug/ml determined by ELISA (QC Test).

Express System: HEK293
Product Tag: C-His-Avi
Activity: Immobilized Biotinylated Human CCR5 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR5 Antibody, hFc Tag with the EC50 of 0.20ug/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Met1-Leu352

Catalog #CR5-HM4N191B

Size

100UG

100UG X 5

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Product Description	Recombinant Biotinylated Human CCR5 Protein-Nanodisc is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Met1-Leu352.
Product Background	CC chemokine receptor 5 (CCR5) is a seven-transmembrane, G protein-coupled receptor (GPCR) which regulates trafficking and effector functions of memory/effector T-lymphocytes, macrophages, and immature dendritic cells. It also serves as the main coreceptor for the entry of R5 strains of human immunodeficiency virus (HIV-1, HIV-2). Chemokine binding to CCR5 leads to cellular activation through pertussis toxin-sensitive heterotrimeric G proteins as well as G protein-independent signalling pathways.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein	CCR5
Synonyms	C-C CKR-5; CC-CKR-5; CCR-5; CHEMR13; CD195; CMKBR5
Accession	P51681
Species	Human
Biotinylated	yes
Amino Acid Range	Met1-Leu352
Molecular Weight	The protein has a predicted MW of 44.5 kDa.
Activity	Immobilized Biotinylated Human CCR5 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR5 Antibody, hFc Tag with the EC50 of 0.20ug/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Immobilized Biotinylated Human CCR5 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CCR5 Antibody, hFc Tag with the EC50 of 0.20ug/ml determined by ELISA (QC Test).