Biotinylated Human CXCR5 Nanodisc (CXC-HM1RNB)
  • Express System: HEK293
  • Product Tag: C-His
  • Activity: Immobilized Biotinylated Human CXCR5 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 18.1ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Met1-Phe372
Catalog #CXC-HM1RNB
Regular price $2,165.90
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Biotinylated Human CXCR5 Nanodisc (CXC-HM1RNB) Summary

Product Description

Recombinant Biotinylated Human CXCR5 Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Phe372.

Product Background

CXCR5 is a serpentine receptor implicated in cell migration in lymphocytes and differentiation in leukocytes. It causes MAPK pathway activation and has known membrane partners for signaling. CXCR5 is also expressed in HL-60 cells, a human acute myeloid leukemia line, following treatment with all-trans retinoic acid, which induces differentiation toward a neutrophil-like state. CXCR5 is necessary for this process; differentiation was crippled in CXCR5 knockout cells and enhanced in cells ectopically expressing it.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Biotinylated Human CXCR5 Nanodisc (CXC-HM1RNB) Specifications/Details

Protein
CXCR5
Synonyms
CXC-R5; CXCR-5; MDR-15; MDR15; CD185; BLR1
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Met1-Phe372
Molecular Weight
The protein has a predicted MW of 54.9 kDa.
Activity
Immobilized Biotinylated Human CXCR5 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 18.1ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Biotinylated Human CXCR5 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 18.1ng/ml determined by ELISA (QC Test). Immobilized Biotinylated Human CXCR5 Nanodisc, His Tag at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 18.1ng/ml determined by ELISA (QC Test).
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