Product Description |
Recombinant Biotinylated Human FGFR1 beta (IIIc) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Lys158-Thr355. |
Product Background |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. |
Product Category |
Recombinant Protein |
Protein |
FGFR1 beta (IIIc) |
Synonyms |
FGFR-1; BFGFR; bFGF-R-1; FLT-2;N-sam; CD331; |
Accession |
|
Species |
Human |
Biotinylated |
yes |
Amino Acid Range |
Lys158-Thr355 |
Molecular Weight |
The protein has a predicted MW of 25.23 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Biotinylated Human FGFR1 beta (IIIc), His-Avi Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-FGFR1 Anitibody, hFc Tag with the EC50 of 73.0ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His-Avi |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Biotinylated Human FGFR1 beta (IIIc) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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