Name: Biotinylated Human IL-17A&F Protein (ILF-HM418B)
Brand: KactusBio
SKU: ILF-HM418B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human IL-17A&F Protein (ILF-HM418B)

Immobilized Human IL-17R alpha, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human IL-17A&F, His Tag with the EC50 of 0.30ug/ml determined by ELISA.

Biotinylated Human IL-17A&F on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

The purity of Biotinylated Human IL-17A&F is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-17R alpha, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human IL-17A&F, His Tag with the EC50 of 0.30ug/ml determined by ELISA.
Amino Acid Range: Gly24-Ala155(IL-17A) & Arg31-Gln163(IL-17F)
Recommended Products:
Loading...

Catalog #ILF-HM418B

Size

100UG

500UG

Order by 4pm ET for delivery on:

[{"id":42618368983262,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"ILF-HM418B-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human IL-17A\u0026F Protein (ILF-HM418B) - 100UG","public_title":"100UG","options":["100UG"],"price":57750,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584303235294,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"ILF-HM418B-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human IL-17A\u0026F Protein (ILF-HM418B) - 500UG","public_title":"500UG","options":["500UG"],"price":192500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Biotinylated Human IL-17A&F Protein (ILF-HM418B) Summary

Product Description	Recombinant Biotinylated Human IL-17A&F Protein is expressed as a heterodimer of IL-17A and IL-17F by co-expression in HEK293. Subunit IL-17A cotains no tag and subunit IL-17F is fused with a His tag and a Avi tag at the C-terminus.It contains Gly24-Ala155 (IL-17A) and Arg31-Gln163 (IL-17F).
Product Background	Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold.IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Biotinylated Human IL-17A&F Protein (ILF-HM418B) Specifications/Details

Protein	IL-17A&F
Synonyms	IL-17A;Interleukin-17A;CTLA-8;IL-17;IL-17F;IL24;ML-1;Interleukin-17F
Accession	Q16552-1(IL-17A)&Q96PD4(IL-17F)
Species	Human
Biotinylated	yes
Amino Acid Range	Gly24-Ala155(IL-17A) & Arg31-Gln163(IL-17F)
Molecular Weight	The protein has a predicted MW of 15.1 kDa (IL-17A) and 17.5 kDa (IL-17F). Due to glycosylation, the protein migrates to 16 kDa and 27 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-17R alpha, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human IL-17A&F, His Tag with the EC50 of 0.30ug/ml determined by ELISA.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human IL-17R alpha, hFc Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Human IL-17A&F, His Tag with the EC50 of 0.30ug/ml determined by ELISA.
	Biotinylated Human IL-17A&F on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of Biotinylated Human IL-17A&F is greater than 95% as determined by SEC-HPLC.