Biotinylated Human LAIR2/CD306 Protein (LAI-HM4R2B)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 1.80 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Gln22-Pro152
Catalog #LAI-HM4R2B
Regular price $525.00
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Product Description
Recombinant Biotinylated Human LAIR2/CD306 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Pro152.
Product Background
The leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) shows increased expression during pregnancy and its reduced expression is associated with pregnancy complications. Although LAIR2 was expressed in the human placenta villus and decidua in the first trimester of pregnancy, it was not expressed in mouse tissues. Knockdown of LAIR2 markedly improved cell viability and inhibited the invasive ability of HTR8/SVneo cells.
Product Category
Recombinant Protein
Target
LAIR2/CD306
Synonyms
LAIR-2; CD306; LAIR2; MGC71634; XXbac-BCX535A19.6
Accession
Species
Human
Biotinylated
yes
Amino Acid Range
Gln22-Pro152
Molecular Weight
The protein has a predicted MW of 17 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Bis-Tris PAGE result.
Activity
The affinity constant of 1.80 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Biotinylated Human LAIR2, His-Avi Tag immobilized on CM5 Chip can bind Native Human Collagen I, No Tag with an affinity constant of 1.80 nM as determined in SPR assay (Biacore T200).
Biotinylated Huma LAIR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Biotinylated Huma LAIR2 is greater than 95% as determined by SEC-HPLC.
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