Biotinylated Human LAIR2/CD306 Protein (LAI-HM4R2B)
Catalog: LAI-HM4R2B
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| Product Description | Recombinant Biotinylated Human LAIR2/CD306 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln22-Pro152. |
Product Background |
The leukocyte-associated immunoglobulin-like receptor 2 (LAIR2) shows increased expression during pregnancy and its reduced expression is associated with pregnancy complications. Although LAIR2 was expressed in the human placenta villus and decidua in the first trimester of pregnancy, it was not expressed in mouse tissues. Knockdown of LAIR2 markedly improved cell viability and inhibited the invasive ability of HTR8/SVneo cells. |
Product Category |
Recombinant Protein |
Target |
LAIR2/CD306 |
| Synonyms | LAIR-2; CD306; LAIR2; MGC71634; XXbac-BCX535A19.6 |
Gene/Protein ID |
Q6ISS4-1 |
Species |
Human |
Exact Sequence |
Gln22-Pro152 |
| Molecular Weight | The protein has a predicted MW of 17 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Tris-Bis PAGE result. |
Activity |
The affinity constant of 1.80 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Biotinylated Human LAIR2, His-Avi Tag immobilized on CM5 Chip can bind Native Human Collagen I, No Tag with an affinity constant of 1.80 nM as determined in SPR assay (Biacore T200). |
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The purity of Biotinylated Huma LAIR2 is greater than 95% as determined by SEC-HPLC. |
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Biotinylated Huma LAIR2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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