Canine HE4 Protein (HE4-DM204)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Gly28-Phe124

Catalog: HE4-DM204

$300.00
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Product Description Recombinant Canine HE4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gly28-Phe124.

Product Background

The ovarian cancer biomarker HE4 is known to promote proliferation, metastasis, chemoresistance, and suppression of cytotoxic lymphocytes. HE4 has the ability to affect signaling events and gene expression in multiple cell types of the tumor microenvironment, which could contribute to angiogenesis and altered immunogenic responses in ovarian cancer.

Product Category

Recombinant Protein

Target

HE4

Gene/Protein ID

Q28894

Species

Canine

Exact Sequence

Gly28-Phe124
Molecular Weight The protein has a predicted MW of 37.06 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Tris-Bis PAGE result.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Canine HE4 is greater than 95% as determined by SEC-HPLC.
Canine HE4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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