Product Description |
Recombinant Human CD20/MS4A1 Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Ile141-Ser188. |
Product Background |
B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases. |
Product Category |
Recombinant Protein |
Target |
CD20/MS4A1 |
Synonyms |
MS4A1; CD20; MS4A-1; B1; Bp35; CD20 receptor; CD20S7; CVID5; LEU-16; Ly-44; MS4A2; S7 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ile141-Ser188 |
Molecular Weight |
The protein has a predicted MW of 16.8 kDa same as Bis-Tris PAGE result. |
Activity |
Immobilized Human CD20, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD20 Antibody, hFc Tag with the EC50 of 4.4ug/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Express System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 20mM PB, 10% Glycerol, 0.4M Urea, 1mM GSH, 0.1mM GSSG (pH 7.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Immobilized Human CD20, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CD20 Antibody, hFc Tag with the EC50 of 4.4ug/ml determined by ELISA. |
|
|
Human CD20 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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