• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Cynomolgus M-CSF, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human M-CSF R, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.889 uM as determined in SPR assay (Biacore T200).
  • Amino Acid Range: Glu33-Leu255
Catalog #CSF-CM101
Price
Regular price $280.50
Regular price Sale price $280.50
/
Size
Avantor VWR Fisher Scientific

Order by 4pm ET for delivery on:

Cynomolgus M-CSF/CSF-1 Protein (CSF-CM101) Summary

Product Description

 Recombinant Cynomolgus M-CSF/CSF-1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu33-Leu255.

Product Background

 CSF-1, also known as M-CSF , is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors.CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery | Others

Cynomolgus M-CSF/CSF-1 Protein (CSF-CM101) Specifications/Details

Protein
 M-CSF/CSF-1
Synonyms
 CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim
Accession
Species
 Cynomolgus
Biotinylated
 no
Amino Acid Range
 Glu33-Leu255
Molecular Weight
 The protein has a predicted MW of 26.26 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Cynomolgus M-CSF, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human M-CSF R, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). The affinity constant of 0.889 uM as determined in SPR assay (Biacore T200).
Product Tag
 C-His

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Cynomolgus M-CSF R, His Tag immobilized on CM5 Chip can bind Cynomolgus M-CSF, His Tag with an affinity constant of 0.889 uM as determined in SPR assay (Biacore T200). Cynomolgus M-CSF R, His Tag immobilized on CM5 Chip can bind Cynomolgus M-CSF, His Tag with an affinity constant of 0.889 uM as determined in SPR assay (Biacore T200).
Immobilized Cynomolgus M-CSF, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human M-CSF R, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test). Immobilized Cynomolgus M-CSF, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human M-CSF R, hFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test).
Cynomolgus M-CSF on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus M-CSF on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Other Available Proteins:
Finding available proteins...
Related Products

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recommended Products

Loading...
Recently viewed